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What Is The Cause of Heart Disease?

A Multi-Part Series by Dr. Malcolm Kendrick, M.D.

What Causes Heart Disease? - Heart disease is defined as the thickenings and narrowings in the larger arteries, the arteries that supply blood to the heart, and the main arteries that supply blood to the brain. Click Here to Read

What Causes Heart Disease? - Part II - Heart disease is a complex issue, alternative hypotheses have been proposed for cardiovascular disease and they need to be fully examined. Click Here to Read

What Causes Heart Disease? - Part III - In most diseases, it's best to start at the beginning and work forwards. This should be the case with cardiovascular disease (CVD) too. However, for complex reasons, the starting point was at the end, and then working backwards. The main reason for this is to start with certainty. Click Here to Read

What Causes Heart Disease? - Part IV - You cannot possibly establish potential causes heart disease, until you are clear about the underlying process. Click Here to Read

What Causes Heart Disease? - Part V - The first stage of cardiovascular disease is damage to the endothelium. The single layer of cells lining the arteries. Click Here to Read

What Causes Heart Disease? - Part VI - Heart disease is really a disease of the larger arteries in the body. Essentially it is a build-up of atherosclerotic plaques (thickenings and narrowings) in the arteries. This could more accurately defined as cardiovascular disease (CVD), in that it can affect all large arteries, not just the arteries in the heart, or neck. Click Here to Read

What Causes Heart Disease? - Part VII - If you're going to understand heart disease, you must be able to link all causes into a single process that fits all of the facts. If you cannot do this, you're stumbling around in the dark. Simply stating the cause is multifactorial adds nothing. Click Here to Read

What Causes Heart Disease? - Part VIII - The healing process. In short, progression is not inevitable. Plaques can shrink down in size, the smooth muscle proliferation reversed and endothelial function restored. Click Here to Read

What Causes Heart Disease? - Part IX - Click Here to Read

What Causes Heart Disease? - Part X - A summary of the calcification of the arteries. - Click Here to Read

What Causes Heart Disease? - Part XI - Click Here to Read

What Causes Heart Disease? - Part XII - Click Here to Read

What Causes Heart Disease? - Part XIII - "However, if you believe that CVD is due to inflammation, then the world’s most potent anti-inflammatory agents ought to decrease CVD risk. Instead, it increases it by at least 400%. [Far more in some studies]...However, it is not a cause, and if you try to reduce inflammation you will almost certainly increase the risk of CVD, not decrease it. Ergo. Inflammation is sign of active CVD. That is all." - Click Here to Read

What Causes Heart Disease? - Part XV - Click Here to Read

What Causes Heart Disease? - Part XVII - Click Here to Read

What Causes Heart Disease? - Part XVIII - Click Here to Read


P.S. When Does Heart Disease Begin? - by Dr. Peter Attia, M.D. - Click Here to Read

P.P.S. "Greater Cholesterol Lowering Increases the Risk of Death" - "The Minnesota Coronary Experiment (MCE), a randomized controlled trial conducted in 1968-73, was the largest (n=9570) and perhaps the most rigorously executed dietary trial of cholesterol lowering by replacement of saturated fat with vegetable oil rich in linoleic acid. The MCE is the only such randomized controlled trial to complete post-mortem assessment of coronary, aortic, and cerebrovascular atherosclerosis grade and infarct status and the only one to test the clinical effects of increasing linoleic acid in large prespecified subgroups of women and older adults." - Click Here to Read